Mangosteen Compound Levels in the Decoction Preparation of Mangosteen Rind (Garcinia mangostanaL.)

Abstract

Mangosteenrind(Garcinia mangostana L.) can be used in herbal preparations in the form of decocta. The main content of the active compound in mangosteenrind is ?-mangostin. This study aims to determine the levels of ?-mangostin compounds in the decocta preparations of mangosteenrind by High-Performance Liquid Chromatography (HPLC) method.This research was carried out by making decocta preparationsof mangosteen rind (Gacinia mangostana L.) using a water solvent. The determination of levels used the HPLC method with the C18 stationary phase, methanol mobile phase: 0.1% formic acid in water (75:25), and UV detection. The determination of the standard curve was done with a standard compound curve to calculate the concentration of ?-mangostin in the decocta preparations of mangosteen rind.The results showed that the levels of ?-mangostin in the decocta preparations of mangosteen rind were (0.2644 ± 8.3067x10-2)%.

Keywords: Garcinia mangostana L., ?-mangostin, decocta, HPLC