Possibility the Co-Infective Participation of Helicobacter Pylori in Dermal Manifestations of Lyme Borreliosis

Authors

  • Bogdanka Andric
  • Milan Jovanovic
  • Milena Đurovic
  • Stefan Kecina

Abstract

At the end of 19th and the beginning of the 20th century, medical science progress contributed pre-optimistic insights that infectious diseases are going to become a past, which only the history and past heroes will remind us on (1). In contrary, in 21st century, infectious diseases enter into their renaissance (2, 3). It is confirmed by modern medical praxis and science. Numerous proves and hypothesis indicate the possibility of an action of different infectious agenses in mutual immunopathogenetic basis of many diseases (4-7). They are responsible for restitution of chronic infections, start up of immune, autoimmune, malignant mechanisms of infections / co-infections. They represent huge and complex diagnostic, differential-diagnostic, therapeutic problems and increasing danger towards human health and life (8-11).
One of the most significant characteristics of borrelia burgdorferi (bb), as a cause of Lyme borreliosis (LB), is the possibility of establishment co-infectious relations with numerous microorganisms from transmissive arthropod zoonosis complex (TAZ) in natural reservoirs, vectors, human infections, as well as capability to reactivate numerous, latent microorganisms within infected organism, based on its own immunological competitiveness (12, 13, 14).
Discovery of correlation between bb. and Helicobacter pylori (Hp), the main cause of chronic and malignant diseases gastrointestinal tract (GIT) and outside GIT, drew the attention of many researchers in the world (15). That encouraged us, in 2002-2017 period of time, to dedicate one segment of examination of LB towards detection of patients who are cases of etiologically simultaneous proven presence and eventually correlation of bb and Hp.
Between 2012 and 2017, on Infective diseases Clinics in Podgorica, 406 patients with etiologically confirmed LB diagnosis were examined, of which 268 patients were detected to have simultaneous presence of Hp, too.

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Published

2020-03-28

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Articles